McAleer J K, Gerson L W, McMahon D, Geller L
Department of Urology, Northeastern Ohio Universities College of Medicine, Akron.
Urology. 1993 Feb;41(2):111-2. doi: 10.1016/0090-4295(93)90158-7.
The purpose of this randomized, controlled, clinical trial was to determine the effect of the digital rectal examination (DRE) on the prostate-specific antigen (PSA) serum levels in view of conflicting literature reports and screening methods and misconceptions by physicians. We showed that the DRE had no clinically important effect on PSA values twenty-four hours later. The mean PSA rose from 1.57 to 1.62 ng/mL, similar to the controls. Ejaculation had no meaningful effect on the serum PSA values.
鉴于文献报道相互矛盾、筛查方法各异以及医生存在误解，本随机对照临床试验的目的是确定直肠指检（DRE）对前列腺特异性抗原（PSA）血清水平的影响。我们发现，24小时后DRE对PSA值没有临床显著影响。PSA的平均值从1.57 ng/mL升至1.62 ng/mL，与对照组相似。射精对血清PSA值没有显著影响。
