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双相型和单相型滑膜肉瘤的细针穿刺抽吸活检细胞学检查。附两例报告。

Aspiration cytology of biphasic and monophasic synovial sarcoma. A report of two cases.

作者信息

Aisner S C, Seidman J D, Burke K C, Young J W

机构信息

Department of Pathology, University of Maryland School of Medicine, Baltimore.

出版信息

Acta Cytol. 1993 May-Jun;37(3):413-7.

PMID:7684548
Abstract

Two cases of synovial sarcoma diagnosed by aspiration cytology are described. A 15-year-old, athletic female presented with a tender midthigh mass clinically thought to be a hematoma. Aspiration cytology revealed numerous clusters of spindle cells admixed with small groups of epithelial cells. Cytokeratin and vimentin stains were positive in the epithelial and spindle components, respectively. Resection of the mass revealed a biphasic synovial sarcoma. Second, a 53-year-old male presented with a recurrent soft tissue mass 10 years after synovial sarcoma of the knee had been resected. Aspiration cytology revealed neoplastic spindle cells. Cytokeratin and vimentin preparations showed focal positivity. Resection revealed a predominantly monophasic synovial sarcoma. These cases demonstrate the utility of aspiration cytology in diagnosing both unsuspected and recurrent synovial sarcoma.

摘要

本文描述了两例经细针穿刺细胞学诊断为滑膜肉瘤的病例。一名15岁的运动型女性,大腿中部出现压痛性肿块,临床考虑为血肿。细针穿刺细胞学检查显示大量梭形细胞簇与少量上皮细胞混合存在。细胞角蛋白和波形蛋白染色分别在上皮成分和梭形成分中呈阳性。肿块切除后显示为双相滑膜肉瘤。第二例,一名53岁男性,在膝关节滑膜肉瘤切除10年后出现复发性软组织肿块。细针穿刺细胞学检查发现肿瘤性梭形细胞。细胞角蛋白和波形蛋白染色显示局灶性阳性。切除后显示主要为单相滑膜肉瘤。这些病例证明了细针穿刺细胞学在诊断意外发现的和复发性滑膜肉瘤中的实用性。

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