De Rosa G, Guarino M, Di Prisco B, D'Armiento M
Istituto di patologia, II Facoltà di medicina e chirurgia, Università degli Studi di Napoli.
Pathologica. 1993 Jan-Feb;85(1095):113-21.
Malignant melanoma of soft part. Report of two cases with unusual histological features. Two examples of malignant melanoma of soft parts (clear cell sarcoma) are reported. In the first case the tumor cells showed predominantly eosinophilic cytoplasms; positive staining for S-100 protein has been observed immunohistochemically in the majority of the tumor cells. The second case, in recurrent lesion, showed a prominent "balloon cell" transformation of tumor cells. The clinico-pathologic picture, differential diagnosis and histogenetic problems are also discussed.
软组织恶性黑色素瘤。两例具有不寻常组织学特征的病例报告。报告了两例软组织恶性黑色素瘤(透明细胞肉瘤)。第一例中,肿瘤细胞主要表现为嗜酸性细胞质;免疫组织化学观察发现大多数肿瘤细胞S-100蛋白染色呈阳性。第二例复发病变中,肿瘤细胞呈现出显著的“气球样细胞”转变。文中还讨论了临床病理表现、鉴别诊断及组织发生问题。