LaMontagne M P, Ao M S, Markovac A, Menke J R
J Med Chem. 1976 Mar;19(3):360-5. doi: 10.1021/jm00225a003.
Based upon the antimalarial activities demonstrated by compounds I and II a series of amino ethers represented by structures III-VI was synthesized. These structures incorporated several modifications of compound II. The compounds prepared displayed no activity in either the Rane P. berghei mouse screen or the Rane P. gallinaceum sporozoite-induced chick test.
基于化合物I和II所显示的抗疟活性，合成了一系列以结构III - VI表示的氨基醚。这些结构对化合物II进行了若干修饰。所制备的化合物在兰氏伯氏疟原虫小鼠筛选试验或兰氏鸡疟原虫子孢子诱导的雏鸡试验中均无活性。
