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Racial differences in maternal serum human chorionic gonadotropin and unconjugated oestriol levels.

作者信息

Kulch P, Keener S, Matsumoto M, Crandall B F

机构信息

Department of Psychiatry, University of California, Los Angeles 90024.

出版信息

Prenat Diagn. 1993 Mar;13(3):191-5. doi: 10.1002/pd.1970130306.

DOI:10.1002/pd.1970130306
PMID:7685088
Abstract

We assayed maternal serum samples from 134 black and 268 white women from 16 to 18 weeks of gestation for intact human chorionic gonadotropin (hCG), and unconjugated oestriol (uE3). Serum from women with high (> or = 2.5 MOMs) or low (risk for Down syndrome > or = 1/365) maternal serum alpha-fetoprotein (MSAFP) levels were excluded. After correcting for maternal weight, we found that median hCG levels were 16 per cent higher in black women but uE3 levels were not significantly different. These results confirm three other studies for hCG and one study for uE3. Corrections are recommended for both maternal serum hCG and AFP before calculating the risk for Down syndrome in black women.

摘要

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