Hansen E S
Institute of Social Medicine, University of Copenhagen, Denmark.
Am J Ind Med. 1993 May;23(5):811-21. doi: 10.1002/ajim.4700230514.
The aim of this study was to investigate a possible relationship between occupational exposure to vehicle exhaust and cancer risk. For this purpose, a cohort of 14,225 truck drivers was followed throughout a ten-year period with regard to cause-specific mortality. Comparisons were made with another cohort of unskilled male laborers. Both of the occupational groups compared were identified at a census and no supplementary data on individual exposure history were available. The study showed an increased mortality for lung cancer (standardized mortality ratio (SMR) 160, 95% confidence interval (CI) 126-200) and multiple myeloma (SMR 439, 95% CI 142-1,024). It seems likely that exposure to diesel exhaust has contributed to the increased lung cancer risk observed. The possible relationship between multiple myeloma and certain constituents of vehicle exhaust may be worth attention in future investigations.
本研究的目的是调查职业性接触汽车尾气与癌症风险之间可能存在的关系。为此，对一组14225名卡车司机进行了为期十年的特定病因死亡率跟踪调查。与另一组非技术男性劳动者进行了比较。所比较的两个职业群体均在一次人口普查中确定，且没有关于个人接触史的补充数据。该研究显示肺癌死亡率增加（标准化死亡比（SMR）为160，95%置信区间（CI）为126 - 200）以及多发性骨髓瘤死亡率增加（SMR为439，95%CI为142 - 1024）。接触柴油尾气似乎导致了所观察到的肺癌风险增加。多发性骨髓瘤与汽车尾气某些成分之间的可能关系在未来的调查中可能值得关注。
