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一项关于丹麦烟民的死亡率研究。

A mortality study of Danish stokers.

作者信息

Hansen E S

机构信息

Institute of Social Medicine, University of Copenhagen, Denmark.

出版信息

Br J Ind Med. 1992 Jan;49(1):48-52. doi: 10.1136/oem.49.1.48.

Abstract

This study was set up to investigate whether work as a stoker is associated with an increased risk of specific malignant neoplasms. For this purpose, a cohort of 2777 male stokers was followed up through a 10 year period with regard to cause specific mortality. Comparisons were made with another cohort of unskilled male workers in physically demanding jobs. The mortality of the stokers was significantly increased for lung cancer (standardised mortality ratio (SMR) 145, 95% confidence interval (95% CI) 110-186) and for multiple myeloma (SMR 388, 95% CI 106-994). Also, increases were seen for cancer of the urinary organs and cancer of the mouth and throat. The combustion products to which the stokers have been exposed comprise several carcinogenic agents including polycyclic aromatic hydrocarbons, benzene, arsenic, and radionuclides. It seems likely that the occupational exposure of stokers has contributed to their excess cancer mortality.

摘要

本研究旨在调查司炉工作是否与特定恶性肿瘤风险增加有关。为此,对2777名男性司炉工组成的队列进行了为期10年的特定病因死亡率随访。与另一组从事体力要求较高工作的非技术男性工人进行了比较。司炉工的肺癌死亡率显著增加(标准化死亡比(SMR)为145,95%置信区间(95%CI)为110 - 186),多发性骨髓瘤死亡率也显著增加(SMR为388,95%CI为106 - 994)。此外,泌尿器官癌和口腔咽喉癌的死亡率也有所上升。司炉工接触的燃烧产物包含多种致癌物质,包括多环芳烃、苯、砷和放射性核素。司炉工的职业暴露似乎导致了他们额外的癌症死亡率。

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本文引用的文献

2
Radiation-induced myelomatosis.放射性骨髓瘤
N Engl J Med. 1981 Jan 22;304(4):204-10. doi: 10.1056/NEJM198101223040404.
9
Malignancies due to occupational exposure to benzene.职业性接触苯所致恶性肿瘤
Am J Ind Med. 1985;7(5-6):395-402. doi: 10.1002/ajim.4700070506.

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