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高度多聚唾液酸化的神经细胞黏附分子(NCAM)在发育中和成年大鼠脊髓中的表达。

Highly polysialylated NCAM expression in the developing and adult rat spinal cord.

作者信息

Seki T, Arai Y

出版信息

Brain Res Dev Brain Res. 1993 May 21;73(1):141-5. doi: 10.1016/0165-3806(93)90056-g.

DOI:10.1016/0165-3806(93)90056-g
PMID:7685664
Abstract

The expression of a highly polysialylated neural cell adhesion molecule (NCAM-H) appeared in motor neurons, presumptive commissural neurons and floor plate at embryonic day 12, and then spread throughout the spinal cord during late embryonic and early postnatal stages. In the adult stage, the expression almost disappeared, but remained in the superficial laminae of the dorsal horn, the lateral spinal nucleus and the area around the central canal. These results suggest that the NCAM-H expression of the spinal cord is involved in the developmental events and possibly in the processing system of somatic and/or visceral information during the adult stage.

摘要

高度多唾液酸化神经细胞黏附分子(NCAM-H)在胚胎第12天出现在运动神经元、假定的连合神经元和底板中,然后在胚胎后期和出生后早期扩散到整个脊髓。在成年阶段,其表达几乎消失,但仍存在于背角浅层、脊髓外侧核和中央管周围区域。这些结果表明,脊髓中NCAM-H的表达参与了发育过程,并且可能在成年阶段参与了躯体和/或内脏信息的处理系统。

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