Mimata C, Itoyama Y, Kuratsu J, Uemura S, Fujioka S, Ushio Y
Department of Neurosurgery, Kumamoto University Medical School.
Neurol Med Chir (Tokyo). 1993 May;33(5):312-5. doi: 10.2176/nmc.33.312.
A 44-year-old female presented with anaplastic astrocytoma of the right temporal lobe which had destroyed the skull base and extended extracranially. Histologically, the extracranial portion of the tumor was astrocytoma with desmoplastic reaction. She was treated by subtotal tumor removal, radiation therapy, and chemotherapy, but died of meningeal dissemination. Spontaneous extradural extension of malignant glioma is rare and always fatal.
一名44岁女性,患有右侧颞叶间变性星形细胞瘤,该肿瘤已破坏颅底并向颅外扩展。组织学检查显示,肿瘤的颅外部分为伴有促纤维增生反应的星形细胞瘤。她接受了肿瘤次全切除、放射治疗和化疗,但最终死于脑膜播散。恶性胶质瘤自发性硬膜外扩展罕见且往往致命。