Horiuchi T, Osawa M, Itoh N, Kobayashi S, Nitta J, Hongo K
Department of Neurosurgery and Pathology, Shinshu University School of Medicine, Matsumoto, Japan.
Surg Neurol. 1996 Jul;46(1):42-6. doi: 10.1016/0090-3019(96)00037-7.
A rare case of glioblastoma multiforme with oral extension is presented in a 41-year-old female. She underwent two surgical treatments and both radiotherapy and chemotherapy for the right temporoparietal glioblastoma multiforme. A follow-up computed tomographic scan and magnetic resonance imaging demonstrated destruction of the temporal base and extradural extension of the tumor into the orbital, nasal, and oral cavities. This is the first report of the oral extension of glioblastoma multiforme. The mechanism for the extradural extension is discussed.
本文报告了一例41岁女性多形性胶质母细胞瘤侵犯口腔的罕见病例。她因右侧颞顶叶多形性胶质母细胞瘤接受了两次手术治疗以及放化疗。随访计算机断层扫描和磁共振成像显示颞骨底部破坏,肿瘤硬膜外扩展至眼眶、鼻腔和口腔。这是多形性胶质母细胞瘤侵犯口腔的首例报告。文中讨论了硬膜外扩展的机制。