Fioravanti A, Franci A, Gelli R, Minari C, Montemerani M, Moscato P, Marcolongo R
Istituto di Reumatologia, Università degli Studi di Siena.
Clin Ter. 1993 May;142(5):453-7.
The above study was undertaken in order to evaluate the efficacy of intra-articular somatostatin in rheumatoid arthritis. Twelve patients were enrolled and all of them concluded the experiment of three consecutive intra-articular somatostatin injections of 750 mcg at two-weekly intervals. All patients reported a statistically significant reduction in painful symptomatology, particularly of pain during active movement, pain at climbing stairs, and morning stiffness. In one patient, telethermography revealed complete subsidence of articular inflammation. There were neither local nor systemic side effects.
上述研究旨在评估关节腔内注射生长抑素治疗类风湿性关节炎的疗效。招募了12名患者，他们均完成了连续3次关节腔内注射750微克生长抑素的实验，注射间隔为两周。所有患者报告称，疼痛症状在统计学上有显著减轻，尤其是活动时的疼痛、爬楼梯时的疼痛和晨僵。1例患者的远红外线热像图显示关节炎症完全消退。未出现局部或全身副作用。
