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[皮肤试验、针对IgE的毒液特异性抗体及嗜碱性粒细胞组胺释放试验在膜翅目昆虫过敏诊断价值中的评估]

[Evaluation of diagnostic value of skin test, venom specific antibodies against EgE and basophil histamine release test in hymenoptera allergy].

作者信息

Nittner-Marszalska M, Małolepszy J, Medrala W

机构信息

Katedry i Kliniki Chorób Wewnetrzynch i Alergologii AM, Wrocławiu.

出版信息

Pneumonol Alergol Pol. 1993;61(7-8):346-51.

PMID:7691338
Abstract

The study compares results of skin test and assessments of venom specific IgE levels (FAST) in patients with Hymenoptera sting allergic reactions. Results of the two diagnostic methods show considerable correlation. Positive correlation occurred in 90% of the patients (92.4% bee venom sensitive allergic patients and 80% wasp venom sensitive patients). Negative correlation occurred in 2% of the patients. In the remaining 8% of the group the results did not correlate. Basophil histamine release test was performed in 13 patients with allergic reactions after stinging. 77% of the basophil histamine release test results showed positive correlation with the other two tests. No correlation was found between the size skin test, the class of the FAST test, and the result of basophil histamine release test. No relationship was found either, between results of the described test and the severity of sting reaction classified to Mueller scale.

摘要

该研究比较了膜翅目昆虫叮咬过敏反应患者的皮肤试验结果和毒液特异性IgE水平评估(FAST)。两种诊断方法的结果显示出相当程度的相关性。90%的患者出现正相关(92.4%对蜂毒敏感的过敏患者和80%对黄蜂毒敏感的患者)。2%的患者出现负相关。在该组其余8%的患者中,结果不相关。对13例叮咬后发生过敏反应的患者进行了嗜碱性粒细胞组胺释放试验。77%的嗜碱性粒细胞组胺释放试验结果与其他两项试验呈正相关。皮肤试验大小、FAST试验类别与嗜碱性粒细胞组胺释放试验结果之间未发现相关性。在所描述的试验结果与根据穆勒量表分类的叮咬反应严重程度之间也未发现相关性。

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Lack of Correlation between Severity of Clinical Symptoms, Skin Test Reactivity, and Radioallergosorbent Test Results in Venom-Allergic Patients.在毒液过敏患者中,临床症状严重程度、皮肤试验反应性和放射变应原试验结果之间无相关性。
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