1型人类免疫缺陷病毒、2型人类免疫缺陷病毒和猴免疫缺陷病毒之间共有的细胞毒性T淋巴细胞表位
Cytotoxic T lymphocyte epitopes shared between HIV-1, HIV-2, and SIV.
作者信息
Gotch F, Nixon D, Gallimore A, McAdam S, McMichael A
机构信息
Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, U.K.
出版信息
J Med Primatol. 1993 Feb-May;22(2-3):119-23.
PMID:7692055
Abstract
A peptide epitope from the gag protein of SIV and from HIV-1 is described which is presented by a cynomolgus macaque MHC molecule and with HLA B14. Comparisons were drawn between recognition of this peptide and that of a second peptide defined in SIV and HIV-2 which has been reported to be presented by the rhesus macaque molecule MaMuA01 and HLA B53 respectively.
摘要
描述了一种来自猴免疫缺陷病毒（SIV）和人类免疫缺陷病毒1型（HIV-1）gag蛋白的肽表位，其由食蟹猕猴主要组织相容性复合体（MHC）分子和人白细胞抗原B14（HLA B14）呈递。对该肽与另一种在SIV和HIV-2中定义的肽的识别情况进行了比较，据报道后一种肽分别由恒河猴分子MaMuA01和HLA B53呈递。
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