O抗原脂多糖在肺炎克雷伯菌对无菌鸡肠道的体内定植中的作用。
The role of the O-antigen lipopolysaccharide on the colonization in vivo of the germfree chicken gut by Klebsiella pneumoniae.
作者信息
Camprubí S, Merino S, Guillot J F, Tomás J M
机构信息
Departamento de Microbiologïa, Universidad de Barcelona, Spain.
出版信息
Microb Pathog. 1993 Jun;14(6):433-40. doi: 10.1006/mpat.1993.1042.
PMID:7692209
Abstract
We isolated lipopolysaccharide and capsular polysaccharide (K antigen)-defective mutants from two Klebsiella pneumoniae parental strains, and compared their ability to colonize in vivo the germfree chicken gut. The high-molecular weight lipopolysaccharide (LPS) (O antigen) was found necessary for the colonization while the capsular polysaccharide (K2 or K29) was not of importance.
摘要
我们从两株肺炎克雷伯菌亲本菌株中分离出脂多糖和荚膜多糖（K抗原）缺陷型突变体，并比较了它们在无菌鸡肠道内定殖的能力。发现高分子量脂多糖（LPS）（O抗原）对于定殖是必需的，而荚膜多糖（K2或K29）并不重要。
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