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O抗原脂多糖在肺炎克雷伯菌对无菌鸡肠道的体内定植中的作用。

The role of the O-antigen lipopolysaccharide on the colonization in vivo of the germfree chicken gut by Klebsiella pneumoniae.

作者信息

Camprubí S, Merino S, Guillot J F, Tomás J M

机构信息

Departamento de Microbiologïa, Universidad de Barcelona, Spain.

出版信息

Microb Pathog. 1993 Jun;14(6):433-40. doi: 10.1006/mpat.1993.1042.

DOI:10.1006/mpat.1993.1042
PMID:7692209
Abstract

We isolated lipopolysaccharide and capsular polysaccharide (K antigen)-defective mutants from two Klebsiella pneumoniae parental strains, and compared their ability to colonize in vivo the germfree chicken gut. The high-molecular weight lipopolysaccharide (LPS) (O antigen) was found necessary for the colonization while the capsular polysaccharide (K2 or K29) was not of importance.

摘要

我们从两株肺炎克雷伯菌亲本菌株中分离出脂多糖和荚膜多糖(K抗原)缺陷型突变体,并比较了它们在无菌鸡肠道内定殖的能力。发现高分子量脂多糖(LPS)(O抗原)对于定殖是必需的,而荚膜多糖(K2或K29)并不重要。

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