Pullan R D, Scriven M W, O'Dowd J, Edwards A T, Lewis M H
Department of Surgery, East Glamorgan General Hospital, Church Village, Mid Glamorgan, Wales.
HPB Surg. 1993 Aug;6(4):301-7; discussion 307-9. doi: 10.1155/1993/20740.
A case of a malignant pancreatic polypeptide secreting tumour is reported. The tumour was metastatic at presentation at which time it was excised. Pancreatic duct obstruction occurred 3 years after excision causing severe pain on eating. Major palliative surgery, in the form of a pancreatico-jejunostomy, cured the severe symptoms. The patient survives, largely symptom free, over six years after original excision. This case illustrates the need for aggressive management of symptoms in tumours in which long term survival is possible despite locally advanced or metastatic disease.
报告了一例分泌恶性胰多肽的肿瘤病例。该肿瘤在初次就诊时已发生转移,当时进行了切除。切除术后3年出现胰管梗阻,导致进食时剧痛。以胰空肠吻合术形式进行的主要姑息性手术治愈了严重症状。患者在初次切除后存活了六年多,基本没有症状。该病例说明了对于那些尽管存在局部晚期或转移性疾病但仍有可能长期存活的肿瘤,需要积极处理症状。