Paulsson M, Kober M, Freij-Larsson C, Stollenwerk M, Wesslén B, Ljungh A
Department of Medical Microbiology, University of Lund, Sweden.
Biomaterials. 1993 Sep;14(11):845-53. doi: 10.1016/0142-9612(93)90006-n.
A commercially available poly(ether urethane), polyethylene, and modifications of these polymers have been compared with respect to adsorption of fibronectin, fibrinogen and vitronectin. The adhesion of staphylococcal strains (characterized for ability to bind immobilized proteins, cell surface hydrophobicity and charge) was studied by bioluminescence with and without preadsorption of proteins to the surfaces. The least amount of proteins and the fewest bacteria adhered to the amphiphilic surfaces. When polymers were preincubated with plasma or albumin, lower numbers of bacteria adhered, except to Pellethane grafted with PEG 20,000, to which coagulase-negative staphylococci adhered to a higher extent.
已对一种市售聚（醚聚氨酯）、聚乙烯及其聚合物改性材料在纤连蛋白、纤维蛋白原和玻连蛋白吸附方面进行了比较。通过生物发光研究了葡萄球菌菌株（以结合固定化蛋白的能力、细胞表面疏水性和电荷为特征）在有或没有蛋白质预吸附到表面的情况下的粘附情况。两亲性表面上吸附的蛋白质最少，粘附的细菌也最少。当聚合物与血浆或白蛋白预孵育时，除了接枝有20,000聚乙二醇的聚醚氨酯（凝固酶阴性葡萄球菌在其上有较高程度的粘附）外，粘附的细菌数量较少。
