Ghione S, Balzan S, Braus S, Montali U, Bruno J
CNR Institute of Clinical Physiology, Pisa, Italy.
Eur J Histochem. 1993;37(3):273-6.
Several lines of evidence suggest the existence, in mammalian body fluids and tissue extracts, of an as yet unidentified endogenous digitalis-like factor with potential cross-immunoreactivity with digitalis. Using anti-digoxin antibodies, we found preliminary immunohistochemical evidence of digoxin-like immunoreactivity in several human tissues. Strong reactivity was found in the adrenal cortex, which may thus represent a site of production of this endogenous factor.
多项证据表明，在哺乳动物的体液和组织提取物中存在一种尚未明确的内源性洋地黄样因子，它可能与洋地黄有交叉免疫反应性。利用抗地高辛抗体，我们在几个人体组织中发现了地高辛样免疫反应性的初步免疫组化证据。在肾上腺皮质中发现了强烈的反应性，因此肾上腺皮质可能是这种内源性因子的产生部位。
