Lupret V, Smiljanić D
Department of Neurosurgery, Sestre Milosrdnice University Hospital, Zagreb.
Acta Med Croatica. 1993;47(1):27-40.
Cranial base lesions present a great challenge even to the most skilled neurosurgeon due to the difficulty of gaining access to the cranial base, the complex anatomical relations, hips of neurovascular structures involved in the pathology of the cranial base and bone destruction caused by tumors leaving intracranial space open to the respiratory and digestive tracts. With continuous advancements in microsurgical techniques and neuroradiological imaging, the removal of cranial base lesions has became a reality. Mortality rates of 50% or greater are today reduced to 10%, and previously very high morbidity rates today are acceptably low. The greatest acknowledgement in the advancement of cranial base lesions management must be given to the teamwork of neurosurgeons, radiologists, head and neck surgeons, otorhinolaryngologists and neuroophthalmologists.
颅底病变对即使是最熟练的神经外科医生来说也是一项巨大的挑战，这是因为进入颅底存在困难、解剖关系复杂、颅底病变所涉及的神经血管结构繁多，以及肿瘤导致的骨质破坏使颅内空间与呼吸道和消化道相通。随着显微外科技术和神经放射影像学的不断进步，切除颅底病变已成为现实。如今，50%或更高的死亡率已降至10%，而且以前非常高的发病率如今也已低至可接受的水平。在颅底病变治疗进展方面，最大的功劳必须归功于神经外科医生、放射科医生、头颈外科医生、耳鼻咽喉科医生和神经眼科医生的团队合作。
