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[不同时长运动减少期间大鼠血浆蛋白组分]

[Blood plasma protein fractions in rats during hypokinesia of various durations].

作者信息

Gritsuk A I

出版信息

Aviakosm Ekolog Med. 1993 Jan-Feb;27(1):59-64.

PMID:7693127
Abstract

The studies indicated that the total content of blood plasma protein in the rats decreases on Days 3, 10 and 30 of hypokinesia and returns to norm on Days 70-140. Albumen concentration increases on Day 3, decreases on Day 10 and normalizes during subsequent days of hypokinesia. The level of alpha-1 globulins reduces on Days 3, 10, increases on Days 30, 70 and normalizes on Days 140 of an exposure. Beta-globulin content decreases on Days 3, 10, 70 and 140 of hypokinesia and level of gamma-globulins also reduces on Days 3 and 30 of hypokinesia and exceeds control values on Days 10, 70 and 140 of immobilization. Since metabolism of the main mass of blood plasma proteins is under hormonal control and their synthesis occurs predominantly in the cells of liver and lymphoid system the data obtained are discussed with regard to the peculiarities of hormonal balance and energy metabolism of the immobilized body.

摘要

研究表明,大鼠血浆蛋白总含量在运动减少第3天、第10天和第30天下降,并在第70 - 140天恢复正常。白蛋白浓度在第3天升高,第10天降低,并在运动减少的后续天数恢复正常。α - 1球蛋白水平在第3天、第10天降低,在第30天、第70天升高,并在暴露第140天恢复正常。β - 球蛋白含量在运动减少第3天、第10天、第70天和第140天降低,γ - 球蛋白水平在运动减少第3天和第30天也降低,并在制动第10天、第70天和第140天超过对照值。由于血浆蛋白主要成分的代谢受激素控制,且其合成主要发生在肝脏和淋巴系统细胞中,因此结合制动机体激素平衡和能量代谢的特点对所得数据进行了讨论。

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