[耳硬化症患者外淋巴蛋白质组分的研究]
[Studies of perilymph protein fractions in patients with otosclerosis].
作者信息
Svatko L G, Galochkin V I, Reshetnikov N N
出版信息
Vestn Otorinolaringol. 1992 Jan-Feb(1):18-20.
Studies of the blood serum in 20 patients and perilymph in 10 patients with otosclerosis showed stability in concentration of total protein as compared with similar control data obtained from cadavers. In this case proteinograms of the blood serum and perilymph of patients with otosclerosis exhibit a statistically significant decrease in albumin and an increase in globulin fractions mainly at the expense of beta- and gamma-globulins with respect to the control. The data obtained evidence the presence of immunological disorders in patients with otosclerosis.
对20例耳硬化症患者的血清和10例耳硬化症患者的外淋巴进行的研究表明，与从尸体获得的类似对照数据相比，总蛋白浓度稳定。在这种情况下，耳硬化症患者血清和外淋巴的蛋白电泳图显示，与对照组相比，白蛋白在统计学上显著降低，球蛋白组分增加，主要是以β-球蛋白和γ-球蛋白为代价。所获得的数据证明耳硬化症患者存在免疫紊乱。
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