Eiermann T H
Abteilung Transfusionsmedizin der Universität Ulm, BRD.
Beitr Infusionsther. 1993;31:70-3.
Transfusion-associated graft versus host disease (ta-GvHD) is a rare but almost lethal complication of blood transfusion in immunocompromised patients. To prevent ta-GvHD, irradiated blood products should be given to patients at risk: patients after bone marrow transplantation, newborns and children in the 1st year, patients with severe combined immunodeficiency, and patients receiving blood from first-degree relatives. Blood products should be irradiated at least with 30 Gy just before transfusion. With this regime in practice for 4 years, no complications and side effects were seen.
输血相关移植物抗宿主病（ta-GvHD）是免疫功能低下患者输血时罕见但几乎致命的并发症。为预防ta-GvHD，应给有风险的患者输注辐照血液制品：骨髓移植后的患者、1岁以内的新生儿和儿童、严重联合免疫缺陷患者以及接受一级亲属血液的患者。血液制品应在输血前至少用30 Gy进行辐照。该方案实施4年来，未见并发症和副作用。
