Otto V
Neurologisch-Psychiatrische Klinik, Städtischen Klinikums Braunschweig.
Fortschr Neurol Psychiatr. 1993 Sep;61(9):310-2. doi: 10.1055/s-2007-999099.
The idiopathic hypereosinophilic syndrome (HES) is a rare disease characterised by prolonged eosinophilia of undetectable cause and by the presence of varying internal symptoms and frequent neurological signs. We report on a 43-year old man with HES who developed cerebral infarction and organic psychosyndrome. Chemotherapy resulted in lower eosinophil counts and marked improvement of central nervous system dysfunction. We comment on possible pathophysiologic mechanisms of central nervous system involvement in HES.
特发性嗜酸性粒细胞增多综合征（HES）是一种罕见疾病，其特征为原因不明的持续性嗜酸性粒细胞增多，伴有各种不同的内部症状和常见的神经体征。我们报告了一名43岁患有HES的男性患者，他发生了脑梗死和器质性精神综合征。化疗使嗜酸性粒细胞计数降低，中枢神经系统功能障碍显著改善。我们对HES中枢神经系统受累的可能病理生理机制进行了评论。
