皮肤巨细胞透明血管病

Cutaneous giant cell hyalin angiopathy.

作者信息

Martin R W, Lumadue J A, Corio R L, Kalb R L, Hood A F

机构信息

Department of Dermatology, Johns Hopkins University School of Medicine Baltimore, Maryland.

出版信息

J Cutan Pathol. 1993 Aug;20(4):356-8. doi: 10.1111/j.1600-0560.1993.tb01275.x.

DOI:10.1111/j.1600-0560.1993.tb01275.x

PMID:7693779

Abstract

Giant cell hyalin angiopathy (GCHA) is an unusual histologic finding associated with inflammation. The lesion has previously only been reported intraorally and is usually preceded by trauma. We report the first case of cutaneous GCHA. The eosinophilic, amorphous material (so-called "hyalin") stained for light chain products, suggesting that their deposition resulted from a reactive process associated with inflammation.

摘要

巨细胞透明血管病（GCHA）是一种与炎症相关的罕见组织学表现。该病变此前仅在口腔内有报道，通常发生于创伤之后。我们报告首例皮肤GCHA病例。嗜酸性无定形物质（所谓的“透明质”）轻链产物染色阳性，提示其沉积是由与炎症相关的反应过程所致。