Maciejek Z, Niezgodzińska-Maciejek A
Klinicznego Oddziału Neurologicznego 10 Wojskowego Szpitala Klinicznego z Poliklinika, Bydgoszczy.
Neurol Neurochir Pol. 1993 May-Jun;27(3):321-9.
The authors present a prospective assessment of combined treatment with high doses of methylprednisolone intravenously and long term administration (12-18 months) of Isoprinosine. The study included 57 patients with clinically certain diagnosis of multiple sclerosis who were examined 1-5 years after treatment completion. Patients with similar degree of motor function disability served for control. Clinical improvement assessed by the motor disability scale of Kurtzke was obtained in over half the patients with various forms of the disease. The results were best in cases of multiple sclerosis of remittent course and those treated at the beginning of the disease.
作者对大剂量静脉注射甲基泼尼松龙与长期（12 - 18个月）服用异丙肌苷的联合治疗进行了前瞻性评估。该研究纳入了57例临床确诊为多发性硬化症的患者，在治疗结束后1至5年对其进行检查。具有相似运动功能残疾程度的患者作为对照。通过库尔茨克运动残疾量表评估，超过半数患有各种形式疾病的患者获得了临床改善。在缓解期多发性硬化症患者以及疾病初期接受治疗的患者中，结果最佳。
