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小柴胡汤对卡拉胶棉球诱导肉芽肿大鼠血清中酸溶性糖蛋白浓度及肉芽肿形成的影响。

The effect of sho-saiko-to on the concentration of acid soluble glycoprotein in serum and on granuloma formation in carrageenin cotton pellet-induced granuloma rats.

作者信息

Yoshida K, Mizukawa H, Honmura A, Uchiyama Y, Kaku H, Nakajima S, Haruki E

机构信息

Kanagawa Rehabilitation Institute, Japan.

出版信息

Am J Chin Med. 1993;21(2):171-7. doi: 10.1142/S0192415X93000200.

DOI:10.1142/S0192415X93000200
PMID:7694453
Abstract

The effect of sho-saiko-to on the concentration of acid soluble glycoprotein in serum and on the granuloma formation in carrageenin cotton pellet-induced rats was investigated. As a result, a significant negative correlation between the concentration of acid soluble glycoprotein and granuloma weight was observed. Furthermore, both the concentration of acid soluble glycoprotein and the inhibition rate of the granuloma formation were significantly higher in the sho-saiko-to group than in the control group. These results suggest that acid soluble glycoprotein plays an important role in promoting the anti-inflammatory effect of sho-saiko-to.

摘要

研究了小柴胡汤对角叉菜胶棉球诱导的大鼠血清中酸溶性糖蛋白浓度及肉芽肿形成的影响。结果发现,酸溶性糖蛋白浓度与肉芽肿重量之间存在显著的负相关。此外,小柴胡汤组的酸溶性糖蛋白浓度及肉芽肿形成抑制率均显著高于对照组。这些结果表明,酸溶性糖蛋白在促进小柴胡汤的抗炎作用中发挥重要作用。

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