Holsen D S, Harthug S, Myrmel H
Health Service, Bergen National Prison, Norway.
Eur J Clin Microbiol Infect Dis. 1993 Sep;12(9):673-6. doi: 10.1007/BF02009378.
A study was performed in order to determine the prevalence of anti-hepatitis C virus (HCV) antibodies, the risk factors for HCV infection and the markers of hepatic disease in a population of prisoners. Of 101 new prisoners admitted to a Norwegian national prison over a three month period, 70 were included in the study, of whom 32 (46%) were anti-HCV positive. Intravenous drug abuse was the predominant risk factor for HCV infection, although a history of tattooing was found by logistic regression analysis to be a significant risk factor independent of intravenous drug abuse. Most anti-HCV positive prisoners had a history of previous incarcerations. Among the anti-HCV positive subjects, increased alanine aminotransferase (> 50 U/l) was found in 23 (72%). HCV infection was the major cause of hepatic abnormalities in the study population. Only 15 (47%) of the anti-HCV positive prisoners reported knowledge of previous hepatic disease.
为了确定囚犯群体中抗丙型肝炎病毒（HCV）抗体的流行率、HCV感染的危险因素以及肝病标志物，开展了一项研究。在三个月期间入住挪威一所国家监狱的101名新囚犯中，70人被纳入研究，其中32人（46%）抗HCV呈阳性。静脉注射毒品滥用是HCV感染的主要危险因素，不过逻辑回归分析发现纹身史是独立于静脉注射毒品滥用的一个显著危险因素。大多数抗HCV呈阳性的囚犯有过入狱史。在抗HCV呈阳性的受试者中，23人（72%）丙氨酸转氨酶升高（>50 U/l）。HCV感染是研究人群中肝脏异常的主要原因。抗HCV呈阳性的囚犯中只有15人（47%）报告知晓既往有肝病。
