Tsai J C, Petrovich M S, Sadun A A
Doheny Eye Institute, Los Angeles, CA 90033, USA.
Br J Ophthalmol. 1995 Feb;79(2):182-5. doi: 10.1136/bjo.79.2.182.
Both optic nerves were obtained at autopsy from a 28-year-old man with a 2 year history of idiopathic intracranial hypertension who had undergone bilateral optic nerve sheath decompression 14 days before death. Histopathological and ultrastructural examination of the tissue revealed fibroblasts localised to the sites of fenestration. Adipose tissue was also adherent to the optic nerve pia in areas of incised dura. No patent fistula site was observed. It was concluded that filtration of cerebrospinal fluid after optic nerve sheath decompression may occur through an enclosed bleb of fibrosis rather than through an open fistula.
双侧视神经取自一名28岁男性尸检样本，该男性患有特发性颅内高压2年，在死亡前14天接受了双侧视神经鞘减压术。对组织进行组织病理学和超微结构检查发现，成纤维细胞定位于开窗部位。在切开硬脑膜的区域，脂肪组织也附着于视神经软膜。未观察到开放的瘘管部位。得出的结论是，视神经鞘减压术后脑脊液的滤过可能通过封闭的纤维化泡而非开放的瘘管发生。
