Avalosse B, Dupont F, Burny A
Laboratory of Molecular Oncology, Institute Jules Bordet, Université Libre de Bruxelles, Belgium.
Curr Opin Oncol. 1995 Jan;7(1):94-100.
This review looks at various gene therapy strategies that are currently being investigated either in experimental studies or in clinical trials. These approaches attempt to either enhance the antitumor immune response of the host, express conditional toxins specifically in tumor cells, reverse the transformed phenotype of tumor cells, or protect normal tissues against the toxicities of conventional treatments.
本综述探讨了目前正在实验研究或临床试验中进行调查的各种基因治疗策略。这些方法试图增强宿主的抗肿瘤免疫反应，在肿瘤细胞中特异性表达条件毒素，逆转肿瘤细胞的转化表型，或保护正常组织免受传统治疗的毒性影响。
