Shirasaka S, Suzuki M, Endou G, Adachi Y, Taira N
School of Agriculture, Ibaraki University, Japan.
J Vet Med Sci. 1994 Dec;56(6):1213-4. doi: 10.1292/jvms.56.1213.
Ten calves harboring microfilariae (Mf) were injected with ivermectin at a single dose of 200 micrograms/kg body weight. Thereafter, the number of calves harboring Mf was gradually reduced to 7, 2 and 0 by 1, 4 and 12 weeks, respectively and remained negative for microfilariae by 16 weeks after injection. Furthermore, none of 221 goats and sheep injected twice with ivermectin at a dose of 200 micrograms/kg body weight developed setariosis while 17 out of 303 non-injected animals suffered from that disease. Therefore, ivermectin was much effective for the eradication of Mf in calves and the prevention of setariosis in sheep and goats.
给10头感染微丝蚴（Mf）的小牛注射了单剂量为200微克/千克体重的伊维菌素。此后，感染Mf的小牛数量在1周、4周和12周时分别逐渐减少到7头、2头和0头，注射后16周微丝蚴检测仍为阴性。此外，221头山羊和绵羊以200微克/千克体重的剂量注射两次伊维菌素后均未发生丝状虫病，而303头未注射的动物中有17头发病。因此，伊维菌素对消除小牛体内的微丝蚴以及预防绵羊和山羊的丝状虫病非常有效。
