妊娠和未妊娠子宫肌层中的镁和钙浓度。
Magnesium and calcium concentration in the pregnant and non-pregnant myometrium.
作者信息
Cunze T, Rath W, Osmers R, Martin M, Warneke G, Kuhn W
机构信息
Department of Gynecology and Obstetrics, University of Göttingen, Germany.
出版信息
Int J Gynaecol Obstet. 1995 Jan;48(1):9-13. doi: 10.1016/0020-7292(94)02217-8.
OBJECTIVES
To investigate the effect of labor on the magnesium and calcium concentrations in the human myometrium and to compare them with the concentrations in the non-pregnant uterus.
METHOD
Samples of the isthmic part of the uterus were taken from 42 patients not in labor, 31 patients in regular labor during a cesarean section, and 37 premenopausal patients on whom a hysterectomy was performed.
RESULTS
(i) The magnesium concentration dropped significantly during labor; (ii) the calcium concentration in the tissue showed no significant changes during labor; (iii) the magnesium and calcium concentrations were significantly higher during pregnancy; (iv) the distribution of electrolytes in the myometrium differed significantly in the corpus, isthmus and cervix uteri.
CONCLUSIONS
The electrolyte concentration in the myometrium depends on the place of removal. A low magnesium concentration in the pregnant human myometrium could be a cause of premature labor.
目的
研究分娩对人子宫肌层镁和钙浓度的影响，并将其与未孕子宫中的浓度进行比较。
方法
从42例未分娩患者、31例剖宫产术中处于规律宫缩期的患者以及37例接受子宫切除术的绝经前患者中获取子宫峡部样本。
结果
（i）分娩过程中镁浓度显著下降；（ii）组织中的钙浓度在分娩过程中无显著变化；（iii）孕期镁和钙浓度显著更高；（iv）子宫肌层中电解质在宫体、峡部和宫颈的分布存在显著差异。
结论
子宫肌层中的电解质浓度取决于取材部位。妊娠人子宫肌层中镁浓度低可能是早产的一个原因。
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