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腺鳞癌:临床及病理特征

The adenosquamous lung carcinoma: clinical and pathological characteristics.

作者信息

Hofmann H S, Knolle J, Neef H

机构信息

Department of Cardio-Thoracic Surgery, Martin-Luther-University of Halle-Wittenberg, Germany.

出版信息

J Cardiovasc Surg (Torino). 1994 Dec;35(6):543-7.

PMID:7698972
Abstract

The adenosquamous carcinoma is a rare combined tumour of non-small cell lung cancer (NSCLC). The survival prognosis of surgically treated patients with adenosquamous carcinoma and patients with squamous cell carcinoma, large cell carcinoma or adenocarcinoma were compared during a study. Two hundred and seventyfive patients who had been treated surgically because of primary lung cancer in the Department of Thoracic-Surgery at the Martin-Luther-University Halle-Wittenberg between 1980 and 1989 were evaluated. The five year survival study of 172 patients who underwent resection because of squamous cell carcinoma was 45%, the one of patients with adenocarcinoma (n = 84) was 27%. 26% was the five year survival rate of the patients (n = 9) with large cell carcinoma. Of 13 patients (4%) with adenosquamous carcinoma none survived five years after surgical treatment. The two year survival rate was 28%. The presented results demonstrate the poor survival prognosis of patients suffering from adenosquamous carcinoma and ask for an adjuvant therapy.

摘要

腺鳞癌是一种罕见的非小细胞肺癌(NSCLC)联合肿瘤。在一项研究中,对接受手术治疗的腺鳞癌患者与鳞状细胞癌、大细胞癌或腺癌患者的生存预后进行了比较。对1980年至1989年间在马丁 - 路德 - 哈雷 - 维滕贝格大学胸外科因原发性肺癌接受手术治疗的275例患者进行了评估。因鳞状细胞癌接受切除术的172例患者的五年生存率为45%,腺癌患者(n = 84)的五年生存率为27%。大细胞癌患者(n = 9)的五年生存率为26%。13例(4%)腺鳞癌患者术后无一人存活五年。两年生存率为28%。所呈现的结果表明腺鳞癌患者的生存预后较差,需要辅助治疗。

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