Campione A, Ligabue T, Luzzi L, Ghiribelli C, Voltolini L, Paladini P, Di Bisceglie M, D'Agata A, Gotti G
Department of Thoracic and Cardiovascular Surgery, University Hospital Le Scotte, Siena, Italy.
J Cardiovasc Surg (Torino). 2004 Feb;45(1):67-70.
Stage IA non small cell lung carcinoma (NSCLC) represents early cancer and is best treated by surgery. The frequency of recurrence and new primary cancer varies from one report to another while the role of sublobar resection is still debated.
We retrospectively reviewed 121 consecutive patients with pathological stage IA after radical surgery.
In stage IA NSCLC 1-, 3-, 5-year survival rates were 89%, 76% and 66%. Nearly half of the deaths were unrelated to the original cancer. From statistical analysis we did not find any factor indicative of a better prognosis. We did not find any difference in survival between histologic types. Segmentectomy did not show a worse survival rate compared with larger resection.
Survival is neither influenced by the type of resection nor by the histologic types in stage IA. However, we noticed a high incidence of local recurrence, segmentectomy could be a viable choice in patients with cardiopulmonary impairment.
IA期非小细胞肺癌（NSCLC）为早期癌症，最佳治疗方法是手术。不同报告中复发和新发原发性癌症的发生率各不相同，而亚肺叶切除术的作用仍存在争议。
我们回顾性分析了121例接受根治性手术后病理分期为IA期的连续患者。
IA期NSCLC患者的1年、3年、5年生存率分别为89%、76%和66%。近一半的死亡与原发癌症无关。经统计分析，我们未发现任何提示预后较好的因素。我们未发现组织学类型之间的生存率有差异。与更大范围的切除术相比，肺段切除术的生存率并未表现更差。
IA期的生存率既不受切除类型影响，也不受组织学类型影响。然而，我们注意到局部复发的发生率较高，对于有心肺功能损害的患者，肺段切除术可能是一个可行的选择。
