Meigooni A S, Li Z, Mishra V, Williamson J F
Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical School, St. Louis, Missouri 63110.
Med Phys. 1994 Dec;21(12):1983-7. doi: 10.1118/1.597232.
In this study the dosimetric properties of Plastic Water and Solid Water phantom materials are evaluated using Monte Carlo photon transport simulations. In particular, their water-equivalence with respect to absorption and attenuation of photons in the brachytherapy energy range are examined. For the given chemical compositions of the materials, the linear attenuation coefficients were calculated for photons of 1 keV-2 MeV. Moreover, absorbed doses to water in each phantom material were calculated at distances of 0.5-12.0 cm from point sources of 20 keV to 60Co gamma rays. These results show that at low photon energies (below 100 keV), there are substantial differences (up to a factor of 5) between the absorbed dose in Plastic Water and that in liquid water. The differences decrease as photon energy increases, and they become insignificant at 60Co gamma rays, as claimed by the manufacturer. In contrast, calculations show that the difference in absorbed dose in Solid Water from that in liquid water, over the entire range of photon energies employed in this study, is less than 25%. The results of this study demonstrate the necessity of careful dosimetric evaluation of a new phantom material, before its clinical application, particularly in energy ranges outside those referred to by the manufacturer.
在本研究中,使用蒙特卡洛光子输运模拟评估了塑料水和固体水体模材料的剂量学特性。特别地,研究了它们在近距离放射治疗能量范围内光子吸收和衰减方面的水等效性。对于给定的材料化学成分,计算了1 keV至2 MeV光子的线性衰减系数。此外,计算了在距20 keV至60Coγ射线点源0.5至12.0 cm处,每种体模材料中水的吸收剂量。这些结果表明,在低光子能量(低于100 keV)下,塑料水中的吸收剂量与液态水中的吸收剂量之间存在显著差异(高达5倍)。随着光子能量增加,差异减小,并且如制造商所宣称的,在60Coγ射线时差异变得不显著。相比之下,计算表明,在本研究使用的整个光子能量范围内,固体水中的吸收剂量与液态水中的吸收剂量差异小于25%。本研究结果表明,在新的体模材料临床应用之前,特别是在制造商提及的能量范围之外,仔细进行剂量学评估是必要的。