Suppr超能文献

近距离放射治疗应用中塑料水和固体水剂量学特性的比较研究。

A comparative study of dosimetric properties of Plastic Water and Solid Water in brachytherapy applications.

作者信息

Meigooni A S, Li Z, Mishra V, Williamson J F

机构信息

Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical School, St. Louis, Missouri 63110.

出版信息

Med Phys. 1994 Dec;21(12):1983-7. doi: 10.1118/1.597232.

Abstract

In this study the dosimetric properties of Plastic Water and Solid Water phantom materials are evaluated using Monte Carlo photon transport simulations. In particular, their water-equivalence with respect to absorption and attenuation of photons in the brachytherapy energy range are examined. For the given chemical compositions of the materials, the linear attenuation coefficients were calculated for photons of 1 keV-2 MeV. Moreover, absorbed doses to water in each phantom material were calculated at distances of 0.5-12.0 cm from point sources of 20 keV to 60Co gamma rays. These results show that at low photon energies (below 100 keV), there are substantial differences (up to a factor of 5) between the absorbed dose in Plastic Water and that in liquid water. The differences decrease as photon energy increases, and they become insignificant at 60Co gamma rays, as claimed by the manufacturer. In contrast, calculations show that the difference in absorbed dose in Solid Water from that in liquid water, over the entire range of photon energies employed in this study, is less than 25%. The results of this study demonstrate the necessity of careful dosimetric evaluation of a new phantom material, before its clinical application, particularly in energy ranges outside those referred to by the manufacturer.

摘要

在本研究中,使用蒙特卡洛光子输运模拟评估了塑料水和固体水体模材料的剂量学特性。特别地,研究了它们在近距离放射治疗能量范围内光子吸收和衰减方面的水等效性。对于给定的材料化学成分,计算了1 keV至2 MeV光子的线性衰减系数。此外,计算了在距20 keV至60Coγ射线点源0.5至12.0 cm处,每种体模材料中水的吸收剂量。这些结果表明,在低光子能量(低于100 keV)下,塑料水中的吸收剂量与液态水中的吸收剂量之间存在显著差异(高达5倍)。随着光子能量增加,差异减小,并且如制造商所宣称的,在60Coγ射线时差异变得不显著。相比之下,计算表明,在本研究使用的整个光子能量范围内,固体水中的吸收剂量与液态水中的吸收剂量差异小于25%。本研究结果表明,在新的体模材料临床应用之前,特别是在制造商提及的能量范围之外,仔细进行剂量学评估是必要的。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验