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大鼠反射性阴茎勃起所涉及神经通路的生理学证据。

Physiological evidence of neural pathways involved in reflexogenic penile erection in the rat.

作者信息

Rampin O, Giuliano F, Dompeyre P, Rousseau J P

机构信息

Laboratoire de Neurobiologie des Fonctions Végétatives, INRA, Jouey-en-Josas, France.

出版信息

Neurosci Lett. 1994 Oct 24;180(2):138-42. doi: 10.1016/0304-3940(94)90506-1.

DOI:10.1016/0304-3940(94)90506-1
PMID:7700566
Abstract

To elucidate neural pathways responsible for the occurrence of reflexogenic erections, the response of the corpus cavernosum to electrical stimulation of the dorsal nerve of the penis (DNP) was measured in anesthetized, acutely spinalized rats. Stimulation elicited a dramatic increase in intracavernous pressure (ICP). ICP response was decreased by 70% after sectioning the pelvic nerve homolaterally to the stimulated DNP and abolished after bilateral section. ICP response was not impaired by curarization, but its latency was lengthened. Thus we physiologically evidenced a reflex loop independent from supraspinal centers between DNP and the pelvic nerve supporting penile reflexogenic erection.

摘要

为了阐明负责反射性勃起发生的神经通路,在麻醉的急性脊髓损伤大鼠中测量了海绵体对阴茎背神经(DNP)电刺激的反应。刺激引起海绵体内压(ICP)急剧升高。在与受刺激的DNP同侧切断盆神经后,ICP反应降低了70%,双侧切断后则消失。箭毒化不会损害ICP反应,但会延长其潜伏期。因此,我们从生理上证明了在DNP和盆神经之间存在一个独立于脊髓上中枢的反射环路,支持阴茎反射性勃起。

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Physiological evidence of neural pathways involved in reflexogenic penile erection in the rat.大鼠反射性阴茎勃起所涉及神经通路的生理学证据。
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引用本文的文献

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Reflex erection in the rat: reciprocal interplay between hemodynamic and somatic events.大鼠的反射性勃起:血液动力学与躯体事件之间的相互作用。
BMC Urol. 2018 May 8;18(1):36. doi: 10.1186/s12894-018-0352-5.
2
Nitric oxide release in penile corpora cavernosa in a rat model of erection.阴茎勃起大鼠模型中海绵体一氧化氮的释放
J Physiol. 1999 Apr 1;516 ( Pt 1)(Pt 1):261-9. doi: 10.1111/j.1469-7793.1999.261aa.x.
3
Spinal control of penile erection.阴茎勃起的脊髓控制
World J Urol. 1997;15(1):2-13. doi: 10.1007/BF01275150.