Suslova M N, Pavlov A D, Morshchakova E F
Patol Fiziol Eksp Ter. 1994 Oct-Dec(4):37-8.
Hormonal changes were studied in hemopoietic disorders. Phenylhydrazine-induced and acute posthemorrhagic anemias were simulated in male Wistar rats. Radioimmunoassay was used to determine the serum levels of thyroid hormones (thyroxine and triiodothyronine) 2, 6, 12, and 24 hours after erythropoietic stress. There was a time course of changes in the levels of thyroid hormones. Administration of a hemolytic poison caused heterodirectional changes in the concentrations of thyroid hormones: an increase of triiodothyronine and a decrease in thyroxine with their normalization at hour 24. Acute blood letting resulted in a significant reduction in the levels both of triiodothyronine and thyroxine in the first hours after exposure. The same time course in the changes in thyroxine levels was observed in test and control groups.
对造血系统疾病中的激素变化进行了研究。在雄性Wistar大鼠中模拟了苯肼诱导的贫血和急性失血性贫血。采用放射免疫分析法测定红细胞生成应激后2、6、12和24小时血清甲状腺激素（甲状腺素和三碘甲状腺原氨酸）水平。甲状腺激素水平存在时间变化过程。给予溶血性毒物导致甲状腺激素浓度呈异向变化：三碘甲状腺原氨酸增加，甲状腺素减少，24小时时恢复正常。急性放血导致暴露后最初几小时内三碘甲状腺原氨酸和甲状腺素水平均显著降低。在试验组和对照组中观察到甲状腺素水平的相同时间变化过程。
