Shalaev S A, Kaleko S P, Bel'skikh A N, Tulupov A N, Popov V I, Zhukov O I, Men'shikova E A
Vestn Khir Im I I Grek. 1993 Jan-Feb;150(1-2):86-90.
It was shown that plasmapheresis included in the complex program of intensive therapy of patients with acute pyo-septic lesions of the lungs and pleura allowed to effectively arrest manifestations of endotoxicosis and to improve results of treatment of this category of patients. Extracorporeal hemoxygenation of small volumes added to plasmapheresis at the expense of inclusion of dialyzer DIP-02-02 in the extracorporeal contour considerably reinforced the detoxicating effect of plasmapheresis at the expense of nonspecific biotransformation of toxins.
结果表明,在急性肺和胸膜化脓性感染患者强化治疗的综合方案中采用血浆置换术,能够有效遏制内毒素血症的表现,并改善这类患者的治疗效果。通过在体外循环回路中加入DIP-02-02型透析器,在血浆置换术基础上增加小容量体外血液氧合,可通过毒素的非特异性生物转化,显著增强血浆置换术的解毒效果。