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[异种脾生物吸附作为烧伤解毒方法的研究]

[Biohemosorption on xenospleen as a method for detoxication in burns].

作者信息

Iarugskiĭ E E, Garib F Iu, Saidov A A, Karev V A, Nuraliev N A

出版信息

Vestn Khir Im I I Grek. 1994 Jan-Feb;152(1-2):108-12.

PMID:7701723
Abstract

Extracorporal inclusion of the porcine spleen was used in 180 patients with burns of the III A-B-IV degrees with the square area of burns from 25% to 95% of the body surface. The age of the patients was from 1 to 60 years. Critical trauma was diagnosed in 48 patients, supercritical--in 132 patients. The total amount of procedures was 310. Positive dynamics in the course of the burn disease was observed after biohemosorption; decrease of the body temperature, of intoxication delirium symptoms, of respiratory insufficiency. The state of the burn wounds was improved. It was stated that the liver function became better, indicators of nonspecific factors of defense, cellular and humoral links of immunity were increased, a tendency to normalization of lipid metabolism was noted. Positive results were obtained in 43 of 48 with critical trauma. Recovery took place in 52 of 132 patients with supercritical traumas.

摘要

对180例III A - B - IV度烧伤患者采用猪脾脏体外植入法,烧伤面积占体表面积的25%至95%。患者年龄为1至60岁。48例患者被诊断为严重创伤,132例为超严重创伤。总共进行了310次手术。生物血液吸附后,烧伤病程呈现积极变化;体温下降,中毒谵妄症状减轻,呼吸功能不全改善。烧伤创面状况得到改善。肝功能好转,非特异性防御因子指标、免疫细胞和体液环节增强,脂质代谢有趋于正常的倾向。48例严重创伤患者中有43例取得阳性结果。132例超严重创伤患者中有52例康复。

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