[儿童胃十二指肠疾病中胃酶功能与胃癌发生相关的特征]
[Characteristics of enzymatic function of the stomach in gastroduodenal diseases in children with regard to gastric carcinogenesis].
作者信息
Privorotskiĭ V F, Kalinovskiĭ V P, Aleksandrova V A, Guliaeva I V, Bobrov Iu F
出版信息
Vopr Onkol. 1994;40(1-3):36-40.
PMID:7701791
Abstract
The paper deals with a description of the biochemical properties of the isoforms of pepsinogen pepsin of gastric mucosa and blood serum in children suffering from duodenal ulcerative disease as well as in atrophic and subtrophic lesions of gastric mucosa. Atrophic gastritis was found to involve an inhibited biosynthesis of the Ist fraction of pepsinogen while ulcerative-erosive lesions of the gastro-duodenal area--an increased level of the 3rd isoform of pepsinogen.
摘要
本文描述了患有十二指肠溃疡性疾病以及胃黏膜萎缩性和亚营养性病变的儿童胃黏膜和血清中胃蛋白酶原同工型的生化特性。研究发现，萎缩性胃炎涉及胃蛋白酶原第一组分的生物合成受抑制，而胃十二指肠区域的溃疡性糜烂病变则涉及胃蛋白酶原第三种同工型水平升高。
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