Lin M, Chen C C, Hong C C, Lin W S, Cheng Y P
National Health Research Institute, Transfusion Medicine Laboratory, Mackay Memorial Hospital, Taipei, Taiwan, ROC.
Vox Sang. 1994;67(4):372-6. doi: 10.1111/j.1423-0410.1994.tb01276.x.
Transfusion-associated respiratory distress occurred more often in the past in Taiwan but recently only very rarely. From the results of our studies it would appear that the former cases did not represent immune reactions involving red blood cells, serum proteins (especially IgA), HLA or granulocyte-specific antigens. Other causes, such as improper handling of the blood units may have been involved, but further study is also needed to investigate the possibility of the role of cytokine release from leukocytes or other factors. In addition, it appears that both plasma and serum obtained by recalcification of plasma may cause false-positive reactions in the granulocyte microagglutination test.
输血相关的呼吸窘迫在过去的台湾较为常见，但近来极为罕见。从我们的研究结果来看，过去的病例似乎并非涉及红细胞、血清蛋白（尤其是IgA）、人类白细胞抗原（HLA）或粒细胞特异性抗原的免疫反应。可能涉及其他原因，如血液制品处理不当，但也需要进一步研究以探讨白细胞释放细胞因子或其他因素所起作用的可能性。此外，似乎血浆以及通过血浆再钙化获得的血清在粒细胞微凝集试验中可能会引起假阳性反应。
