Monastra Varrica L, Doweck J, Améndola R, Farías R, Schenone L, Bori J, Fiorini A, Musi A O, Corti R E
Sección Esófago-Estómago, Hospital de Gastroenterología, Capital Federal, Argentina.
Acta Gastroenterol Latinoam. 1994;24(4):245-9.
Systemic sclerosis is a collagen disease with high frequency of oesophageal affection, specially if we use manometry as an evaluation method that has a high rate of clinic complication in high rate of patients. The aim of the study was to evaluate the prevalence of the oesophageal affection through the clinical, radiological, endoscopical and manometrical studies and to compare the results with other authors. Between January 1978 and February 1993, we evaluated 101 patients with different clinical types of scleroderma 89 females and 12 males with ages between 16-83 (mean: 49, 19 years). In order to determine systemic sclerosis diagnosis following Masi Rodman criterion's we found from 101 cases 83 had dysphagia (82.2%) motor 66 (65%) organic 17 (34.7%) GER was seem in 41 cases (40.5%). According to Heitz's radiological classification: I: 26 patients (25%) II: 58 patients (52.4%) III: 19 patients (18.8%) IV: 17 patients (16.9%). In reference to Neschis manometric classification we found II 88 (76%) III 77 (76%) In accordance with endoscopical classification we found I: 16 (15.8%); II: 49 (48.5%); III: 19 (18.8%); IV: 17 (16.9%); Although this motor and organic oesophageal alterations have an evident diagnostic value, they have also been referred in another metabolic and collagen diseases but with lesser frequency than was found in the systemic sclerosis by us.
系统性硬化症是一种胶原病，食管受累的发生率较高，特别是当我们使用测压法作为评估方法时，该方法在大量患者中具有较高的临床并发症发生率。本研究的目的是通过临床、放射学、内镜和测压研究评估食管受累的患病率，并将结果与其他作者进行比较。1978年1月至1993年2月期间，我们评估了101例不同临床类型的硬皮病患者，其中89例女性和12例男性，年龄在16 - 83岁之间（平均：49.19岁）。为了按照马西·罗德曼标准确定系统性硬化症的诊断，我们发现101例病例中有83例有吞咽困难（82.2%），其中运动性吞咽困难66例（65%），器质性吞咽困难17例（34.7%）；41例（40.5%）出现胃食管反流。根据海茨的放射学分类：I：26例患者（25%）；II：58例患者（52.4%）；III：19例患者（18.8%）；IV：17例患者（16.9%）。参照内斯基斯的测压分类，我们发现II型88例（76%），III型77例（76%）。根据内镜分类，我们发现I：16例（15.8%）；II：49例（48.5%）；III：19例（18.8%）；IV：17例（16.9%）；尽管这种食管运动和器质性改变具有明显的诊断价值，但在其他代谢性和胶原病中也有报道，不过其发生率低于我们在系统性硬化症中发现的频率。
