Tsujikawa A, Otani A, Takanashi T, Ogura Y
Department of Ophthalmology, Kyoto University Faculty of Medicine, Japan.
Nippon Ganka Gakkai Zasshi. 1995 Feb;99(2):200-3.
We retrospectively studied 255 eyes of 190 diabetic patients who underwent cataract extraction with posterior chamber intraocular lens (IOL) implantation. One hundred forty-six eyes (57.3%) achieved the best visual acuity of 20/30 or better and 221 eyes (86.7%) achieved the acuity of 20/100 or better. Among 161 eyes that were followed up over 6 months, 26 eyes (16%) showed a progression of the retinopathy. Eight eyes developed proliferative retinopathy from non-proliferative retinopathy. The level of glycosylated hemoglobin of the progression group at the time of surgery was significantly higher than that of the non-progression group (8.0 +/- 2.4% vs 6.8 +/- 1.6%, p < 0.05). Sixty-five patients received IOL implantation in one eye. Of these patients, 10 eyes (15%) showed progression of the retinopathy. Seventy percent of the fellow eyes also showed the progression, where as 95% of the non-progression group did not show progression in the fellow eyes. The results suggested that the progression of diabetic retinopathy after IOL implantation was correlated with diabetic control at the time of surgery. Additionally, patients who developed the progression of the retinopathy in pseudophakic eyes frequently showed the progression in the fellow unoperated eyes.
我们回顾性研究了190例接受白内障摘除联合后房型人工晶状体（IOL）植入术的糖尿病患者的255只眼。146只眼（57.3%）达到了20/30或更好的最佳视力，221只眼（86.7%）达到了20/100或更好的视力。在随访超过6个月的161只眼中，26只眼（16%）出现了视网膜病变进展。8只眼从非增殖性视网膜病变发展为增殖性视网膜病变。进展组手术时糖化血红蛋白水平显著高于非进展组（8.0±2.4%对6.8±1.6%，p<0.05）。65例患者单眼植入IOL。在这些患者中，10只眼（15%）出现了视网膜病变进展。70%的对侧眼也出现了进展，而非进展组95%的对侧眼未出现进展。结果表明，IOL植入术后糖尿病视网膜病变的进展与手术时的糖尿病控制情况相关。此外，人工晶状体眼出现视网膜病变进展的患者，其未手术的对侧眼常也出现进展。
