涉及噬菌体T5染色体第一步转移区域的末端冗余杂合子。
Terminal redundancy heterozygotes involving the first-step-transfer region of the bacteriophage T5 chromosome.
作者信息
Fischhoff D, MacNeil D, Kleckner N
出版信息
Genetics. 1976 Feb;82(2):145-59. doi: 10.1093/genetics/82.2.145.
Abstract
Individual progeny of two-factor crosses between A1am and A2am T5 phages give rise to bursts containing more than one type of plaque. The simplest explanation for these mixed bursts is that the A1 and A2 genes are located within the terminally repeated portion of the T5 genome and that the mixed bursts are made by "terminal redundancy heterozygotes". The observation of genetic heterozygosity means that the A1 and A2 genes are repeated intact. This implies that the terminal segments of T5 are genetically interchangeable.
摘要
A1am和A2am T5噬菌体之间双因子杂交的单个后代产生的裂解物中含有不止一种类型的噬菌斑。对于这些混合裂解物最简单的解释是，A1和A2基因位于T5基因组的末端重复部分，并且混合裂解物是由“末端冗余杂合子”产生的。遗传杂合性的观察结果意味着A1和A2基因是完整重复的。这表明T5的末端片段在遗传上是可互换的。
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J Mol Biol. 1964 Oct;10:10-8. doi: 10.1016/s0022-2836(64)80023-1.
3
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