Ricciardelli E, Morgan R F, Lin K Y
Department of Plastic Surgery and Orthopedics, University of Virginia Health Sciences Center, Charlottesville 22908.
Ann Plast Surg. 1995 Jan;34(1):81-3. doi: 10.1097/00000637-199501000-00017.
In utero brachial artery thrombosis leading to neonatal extremity gangrene can occur from a variety of causes. Traditional management has been limited to supportive care, often leading to early amputation. We report a case of a 1-day-old neonate who presented with an in utero brachial artery thrombosis and whose treatment consisted of early, aggressive systemic thrombolytic therapy followed by serial soft-tissue debridement and ultimate skin coverage through cultured epithelial autografts. This resulted in a successfully salvaged and partially functional upper extremity.
子宫内肱动脉血栓形成导致新生儿肢体坏疽可由多种原因引起。传统治疗方法仅限于支持性护理，常导致早期截肢。我们报告一例1日龄新生儿，其患有子宫内肱动脉血栓形成，治疗方法包括早期积极的全身溶栓治疗，随后进行系列软组织清创，最终通过培养的自体上皮移植覆盖皮肤。这使得上肢成功挽救且部分功能得以保留。
