乳头溢液女性患者预后的前瞻性研究。
Prospective study of outcome in women presenting with nipple discharge.
作者信息
Carty N J, Mudan S S, Ravichandran D, Royle G T, Taylor I
机构信息
Breast Unit, Royal South Hants Hospital, Southampton.
出版信息
Ann R Coll Surg Engl. 1994 Nov;76(6):387-9.
In this study, 56 women who presented to the breast clinic with nipple discharge have been reviewed. Patients were selected for surgery by a triple assessment of clinical examination, discharge cytology and breast imaging. Surgical intervention was required in 17 women. Significant pathology was found in 11 cases including five with carcinoma (in situ or invasive). Those women who did not have carcinoma detected at their initial presentation have been reviewed after a minimum of 5 years. None has gone on to develop breast cancer. We conclude that women with nipple discharge, but no positive findings on triple assessment, are not at an increased risk of the development of carcinoma. In addition, nipple discharge spontaneously resolves in 73% of women over a 5 year period.
在本研究中，对56名因乳头溢液到乳腺门诊就诊的女性进行了回顾性分析。通过临床检查、溢液细胞学检查和乳腺影像学检查的三联评估来选择患者进行手术。17名女性需要进行手术干预。在11例中发现了重大病变，其中5例为癌（原位癌或浸润性癌）。那些在初次就诊时未检测出癌症的女性在至少5年后接受了复查。没有人继续发展为乳腺癌。我们得出结论，乳头溢液但三联评估无阳性发现的女性患癌风险并未增加。此外，73%的女性乳头溢液在5年内会自行消退。
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