Schirren J, Cuénoud P F, Bülzebruck H, Krysa S, Branscheid D, Müller K M, Vogt-Moykopf I
Département de Chirurgie, Thoraxklinik Heidelberg-Rohrbach, Allemagne.
Ann Chir. 1994;48(9):852-61.
Or the 3000 patients analyzed in the prospective bronchial carcinoma field study, 1086 were operated between 1984 and 1989. Complete systematic mediastinal lymphadenectomy was performed in 661 patients to assess the PTNM stage as exactly as possible, and to improve prognosis. Lymphadenectomy removes all hylarand mediastinal lymph nodes. Although the operation is technically quite easy on the clearly structured right side, it is more difficult on the left side due to the aortic arch and its branches. The lymph nodes of the upper mediastinum of the left and right side can be completely dissected by mobilizing the aortic arch with the left subclavian artery. In contrast to what is frequently assumed, the histological findings indicate that there is no general pattern of metastatic spread in the lymph nodes. The metastases can leave out varying numbers of lymph nodes craniad as well as caudad. For this reason, the lymph nodes have to be completely resected to ensure a real R0-resection.
在一项前瞻性支气管癌领域研究中分析的3000例患者中,1086例于1984年至1989年间接受了手术。661例患者进行了完整的系统性纵隔淋巴结清扫术,以尽可能准确地评估PTNM分期,并改善预后。淋巴结清扫术切除所有肺门和纵隔淋巴结。虽然在结构清晰的右侧,该手术在技术上相当容易,但由于主动脉弓及其分支,在左侧则更困难。通过游离主动脉弓和左锁骨下动脉,可以完全清扫左右上纵隔的淋巴结。与通常的假设相反,组织学结果表明淋巴结中不存在转移扩散的一般模式。转移灶可跳过不同数量的头侧和尾侧淋巴结。因此,必须完全切除淋巴结以确保真正的R0切除。