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对某一诊所五年期间女性不孕症的患病率及治疗情况进行回顾性研究。

Retrospective review of the prevalence and management of infertility in women in one practice over a five year period.

作者信息

Wilkes S, Jones K

机构信息

Department of Primary Health Care, University of Newcastle upon Tyne.

出版信息

Br J Gen Pract. 1995 Feb;45(391):75-7.

Abstract

BACKGROUND

Subfertility in general practice is a common problem. However, most treatment is initiated in hospital. There may be a role for general practitioners in the treatment of some infertile patients.

AIM

The aim of this study was to investigate the prevalence and management of infertility in women in general practice and to identify a specific cohort of patients potentially suitable for management in primary care.

METHOD

The general practice notes of all women patients between the ages of 16 and 42 years who presented to their general practitioner with an infertility problem in the five years preceding July 1993 were analysed retrospectively. The patients were identified from the computer database of one Durham general practice.

RESULTS

Fifty four cases were identified over the five year period, giving a prevalence of infertility in women in the practice of 15 per 1000 women. Of those who had a definite diagnosis made, 27% had an ovulatory disorder. Women with an ovulatory disorder tended to have a low serum day 21 progesterone level (90%); to present with primary infertility (80%); and to receive clomiphene as first line therapy (80%). The majority of ovulation induction therapy (95%) was initiated in secondary care.

CONCLUSION

Ovulation induction therapy with clomiphene appears to be uncommon in general practice at present. Women requiring ovulation induction therapy may be a cohort of patients suitable for such management in general practice. These patients tend to present with primary infertility and to have a low mid-luteal progesterone level.

摘要

背景

全科医疗中的生育力低下是一个常见问题。然而,大多数治疗是在医院开始的。全科医生在某些不孕患者的治疗中可能发挥作用。

目的

本研究的目的是调查全科医疗中女性不孕症的患病率及管理情况,并确定一组可能适合在初级保健机构管理的特定患者群体。

方法

回顾性分析了1993年7月前五年间因不孕问题就诊于全科医生的所有16至42岁女性患者的全科医疗记录。这些患者是从达勒姆一家全科诊所的计算机数据库中识别出来的。

结果

在这五年期间共识别出54例病例,该诊所女性不孕症的患病率为每1000名女性中有15例。在那些得到明确诊断的患者中,27%患有排卵障碍。患有排卵障碍的女性往往血清第21天孕酮水平较低(90%);表现为原发性不孕(80%);并接受克罗米芬作为一线治疗(80%)。大多数促排卵治疗(95%)是在二级医疗保健机构开始的。

结论

目前在全科医疗中,使用克罗米芬进行促排卵治疗似乎并不常见。需要促排卵治疗的女性可能是适合在全科医疗中进行此类管理的一组患者。这些患者往往表现为原发性不孕,且黄体中期孕酮水平较低。

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本文引用的文献

1
The treatment of psychologic factors in anovulation.无排卵中心理因素的治疗。
Fertil Steril. 1961 Jan-Feb;12:55-66. doi: 10.1016/s0015-0282(16)34026-2.
7
Treatment-independent pregnancy among infertile couples.不孕夫妇的非治疗性妊娠
N Engl J Med. 1983 Nov 17;309(20):1201-6. doi: 10.1056/NEJM198311173092001.
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Effectiveness of treatment for infertility.不孕症的治疗效果。
Br Med J (Clin Res Ed). 1987 Jul 18;295(6591):155-6. doi: 10.1136/bmj.295.6591.155.
10
The epidemiology of infertility in Aberdeen.阿伯丁的不孕症流行病学。
BMJ. 1990 Jul 21;301(6744):148-52. doi: 10.1136/bmj.301.6744.148.

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