Ogino T, Ikehira H, Arimizu N, Moriya H, Wakimoto K, Nishikawa S, Shiratsuchi H, Kato H, Shishido F, Tateno Y
Department of Radiology, University of Chiba, Japan.
Ann Nucl Med. 1994 Nov;8(4):219-24. doi: 10.1007/BF03165023.
In vivo 1H-magnetic resonance imaging (MRI) enabled us to study the distribution of water in living tissues and to document changes in human skeletal muscles during physical exercise. The purpose of the present study was to determine the total muscle water changes after exercise using water in 1H-MR spectroscopy and to compare these changes to the signal intensity change on T2*-weighted images and/or to the T2 value change. Seven young male volunteers were positioned in a 1.5 T Philips MR imaging system. They were then asked to dorsiflex their ankle joint against a 2 kg weight once every 2 seconds for 2 minutes. The peak height of water declined according to the clearance curve after exercise in all seven cases with the 1H-MRS similar to the signal intensity. The increasing rate at peak height of total muscle water exceeded both the signal intensity and the T2 value because the water peak height on the 1H-MRS included the extracellular water. In addition, we measured the changes in signal intensity in both calf muscles after walking race exercise. The time intensity curves were used to draw a clearance curve for each muscle group after exercise. It was possible to discern which muscle was used most from the T2*-weighted image that was obtained once after exercise.
体内1H磁共振成像（MRI）使我们能够研究活组织中的水分分布，并记录体育锻炼期间人体骨骼肌的变化。本研究的目的是使用1H磁共振波谱中的水分来确定运动后肌肉总水分的变化，并将这些变化与T2 *加权图像上的信号强度变化和/或T2值变化进行比较。七名年轻男性志愿者被安置在1.5 T飞利浦MR成像系统中。然后要求他们以每2秒一次的频率，对抗2 kg的重量背屈踝关节，持续2分钟。在所有七个案例中，运动后水的峰高根据清除曲线下降，1H-MRS中的峰高与信号强度相似。总肌肉水分峰高的增加速率超过了信号强度和T2值，因为1H-MRS上的水峰高包括细胞外水。此外，我们测量了竞走运动后双侧小腿肌肉的信号强度变化。时间强度曲线用于绘制运动后每个肌肉组的清除曲线。从运动后立即获得的T2 *加权图像中，可以辨别出使用最多的肌肉。
