Pillitteri J L, Kozlowski L T, Person D C, Spear M E
Program in Bio-behavioral Health, Pennsylvania State University, University Park 16802-6508.
J Subst Abuse. 1994;6(3):315-23. doi: 10.1016/s0899-3289(94)90502-9.
Over-the-counter (OTC) sleep aids are used in greater proportions than benzodiazepines for the treatment of sleep problems, yet limited research has focused on these nonprescription drugs. This article reports the results of two studies that examined the use of OTC sleep aids and alcohol for sleep problems by university students. Of those subjects in both studies who reported sleep problems 1 day per month or more, 6.4% of men and 11.4% of women reported using OTC sleep aids, however, a significantly greater percentage of men reported using alcohol to induce sleep (23.4% vs. 10.9%, p < .008). Future studies on OTC sleep aids are recommended to address a broader range of issues such as potential side effects and at-risk populations, tolerance effects, and individual differences in responsiveness and sensitivity to these drugs.
在治疗睡眠问题时，非处方（OTC）助眠药物的使用比例高于苯二氮䓬类药物，但针对这些非处方药的研究却很有限。本文报告了两项研究的结果，这两项研究调查了大学生使用非处方助眠药物和酒精来解决睡眠问题的情况。在两项研究中，每月至少有一天报告存在睡眠问题的受试者中，6.4%的男性和11.4%的女性报告使用非处方助眠药物，然而，报告使用酒精助眠的男性比例显著更高（23.4%对10.9%，p <.008）。建议未来针对非处方助眠药物的研究解决更广泛的问题，如潜在副作用和高危人群、耐受性影响以及对这些药物反应性和敏感性的个体差异。
