Cristofolini M, Zumiani G, Bauer P, Cristofolini P, Boi S, Micciolo R
Department of Dermatology, S. Chiara Hospital, Trento, Italy.
Melanoma Res. 1994 Dec;4(6):391-4. doi: 10.1097/00008390-199412000-00008.
Dermatoscopy has been reported to give valid information in the differential diagnosis of cutaneous pigmentary lesions. Using a dermatoscopy Delta 10 Heine optotechnique, we evaluated 220 pigmented lesions during a health campaign for the early diagnosis of cutaneous melanoma and compared clinical and dermatoscopic diagnosis. Histologic diagnosis was carried out after removal of the lesions. Sensitivity, specificity, positive predictive value, negative predictive value and overall agreement were evaluated. In our experience clinical and dermatoscopic diagnosis gave similar results; sensitivity and specificity were slightly better for dermatoscopy than for clinical diagnosis. The agreement between clinical and dermatoscopic diagnosis was better in histologically negative lesions. Dermatoscopy is useful in the diagnosis of pigmentary lesions, but clinical diagnosis by experienced dermatological staff, is unreplaceable, especially during a health campaign for the early diagnosis of cutaneous melanoma.
据报道，皮肤镜检查在皮肤色素性病变的鉴别诊断中能提供有效的信息。我们使用Delta 10海涅光学技术皮肤镜，在一项皮肤黑色素瘤早期诊断的健康活动中对220个色素性病变进行了评估，并比较了临床诊断和皮肤镜诊断。病变切除后进行了组织学诊断。评估了敏感性、特异性、阳性预测值、阴性预测值和总体一致性。根据我们的经验，临床诊断和皮肤镜诊断结果相似；皮肤镜检查的敏感性和特异性略优于临床诊断。组织学检查为阴性的病变中，临床诊断和皮肤镜诊断的一致性更好。皮肤镜检查在色素性病变的诊断中很有用，但经验丰富的皮肤科工作人员进行的临床诊断是不可替代的，尤其是在皮肤黑色素瘤早期诊断的健康活动中。
