Ascorbic acid is cytotoxic for pediatric tumor cells cultured in vitro.
作者信息
Medina M A, García de Veas R, Schweigerer L
机构信息
Sektion Onkologie/Immunologie, Universitäts Kinderklinik, Ruprecht-Karls-Universität, Heidelberg, Germany.
出版信息
Biochem Mol Biol Int. 1994 Nov;34(5):871-4.
PMID:7703904
Abstract
2 mM Ascorbic acid has a potent cytotoxic effect on neuroblastoma, osteosarcoma, retinoblastoma, and rhabdomyosarcoma cells cultured in vitro. At a lower concentration (0.2 mM), ascorbic acid remains highly cytotoxic for neuroblastoma, osteosarcoma and retinoblastoma cells, but it has a stimulatory effect on the growth of rhabdomyosarcoma cells.
摘要
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